Specific Protein Determinations Using Immunoelectrophoresis

Abstract

The Laurell ‘rocket’ technique of immunoelectrophoresis has been used to quantitate seven specific serum proteins in a control population of SO healthy persons and in 100 hospital patients. Reference ranges have been established for each protein from data obtained from the control population. For many of the proteins variations due to age and/or sex were observed. Sex hormones, probably oestrogens, were also observed to cause variations in some of the protein concentrations. Data obtained from the hospital patients indicated that further work should prove profitable and could enable specific protein determinations to be useful, both as a diagnostic tool and in following the course of a disease.