A Novel Metalloprotease in Rat Brain Cleaves the Amyloid Precursor Protein of Alzheimer's Disease Generating Amyloidogenic Fragments
- 1 January 1997
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 36 (1), 156-163
- https://doi.org/10.1021/bi961848w
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease InhibitorsPublished by Elsevier ,1996
- Processing of the β‐Amyloid Precursor Protein and Its Regulation in Alzheimer's DiseaseJournal of Neurochemistry, 1995
- Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor proteinJournal of Neuroscience, 1994
- Characterization by radiosequencing of the carboxyl-terminal derivatives produced from normal and mutant amyloid β protein precursorsAmyloid, 1994
- Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.Proceedings of the National Academy of Sciences, 1993
- Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.Proceedings of the National Academy of Sciences, 1992
- Alzheimer amyloid β/A4 peptide binding sites and a possible ‘APP-secretase’ activity associated with rat brain cortical membranesBrain Research, 1991
- Increased release of an amyloidogenic C-terminal Alzheimer amyloid precursor protein fragment from stressed PC-12 cellsJournal of Neuroscience Research, 1991
- Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.Proceedings of the National Academy of Sciences, 1990
- Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissueBiochemical Journal, 1955