Histone genes are clustered but not tandemly repeated in the chicken genome.
Open Access
- 1 May 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (5), 2856-2860
- https://doi.org/10.1073/pnas.78.5.2856
Abstract
The recombinant chicken DNA library was screened for histone genes by using pSp17, a recombinant sea urchin DNA probe containing the H2a and H3 genes of Strongylocentrotus purpuratus. Three of the isolated .lambda. recombinants were analyzed by restriction enzyme mapping and Southern blotting; 1 histone H3 gene-encoding recombinant was further analyzed by DNA sequence determination. The chicken histone genes apparently are not tandemly reiterated, but at the least, several histone genes are physically closely linked in a nonrepetitive arrangement within the chicken genome. The evolutionary implications of this arrangement vs. that seen in Drosophila and sea urchins is discussed.This publication has 23 references indexed in Scilit:
- The programmed switch in lysine-rich histone synthesis at gastrulationCell, 1976
- A simple method for DNA restriction site mappingNucleic Acids Research, 1976
- Histone-Gene Reiteration in the Genome of MouseEuropean Journal of Biochemistry, 1976
- Reiteration frequency of the gene for tissue-specific histone H5 in the chicken genomeNature, 1976
- Histone gene arrangement in the sea urchin, Strongylocentrotus purpuratus.Proceedings of the National Academy of Sciences, 1975
- Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresisBiochemistry, 1975
- Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structuresJournal of Molecular Biology, 1975
- Nucleotide sequence of the rightward operator of phage lambda.Proceedings of the National Academy of Sciences, 1975
- Reiteration frequency of histone coding sequences in manBiochemical and Biophysical Research Communications, 1974
- Reiteration and Clustering of DNA Sequences Complementary to Histone Messenger RNANature New Biology, 1971