Induction of Immune Interferon by Murine Cytomegalovirus
- 1 September 1977
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 155 (4), 611-614
- https://doi.org/10.3181/00379727-155-39861
Abstract
Studies were initiated in mice to develop a model of cell-mediated immunity to murine cytomegalovirus (MCMV). Immune interferon was produced in response to MCMV antigens in cultures of splenic lymphocytes from mice infected 7, 10 and 14 days previously. There was no lymphocyte transformation as measured by antigen-specific enhancement of [3H]thymidine uptake. Lymphocyte transformation in response to phytohemagglutin in (PHA) was transiently suppressed in lymphocytes of MCMV-infected mice.This publication has 3 references indexed in Scilit:
- Interferon and Cytomegalovirus in vivo and in vitro.Experimental Biology and Medicine, 1967
- Studies of Relationship Between Mouse Cytomegalovirus and Interferon.Experimental Biology and Medicine, 1966
- Interferon Production in vitro by Cells Infected with the Murine Salivary Gland Virus.Experimental Biology and Medicine, 1964