Hemagglutination Induced by Aabinosyl-6-Mercaptopurine.

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Abstract
Summary Arabinosyl-6-mercaptopurine, a nucleoside that prolonged the survival of skin homografts, induced non-specific agglutination of either sheep or human red blood cells. The drug was bound to red blood cell stroma and the number of sites occupied on the stroma was determined as approximately 1.2 × 105 per red blool cell for tanned sheep cells and 6.7 × 105 per red blood cell for human type B cells. A heterologous antibody partially inhibited the hemagglutination induced by arabinosyl-6-mercaptopurine.