Cross-reaction of a monoclonal anti-filaggrin antibody with glycogen
- 1 January 1987
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 87 (6), 597-600
- https://doi.org/10.1007/bf00492476
Abstract
A mouse monoclonal anti human filaggrin antibody was found to bind keratohyaline granules of normal epidermis as well as of premalignant and malignant lesions in formalin-fixed tissue sections. In addition, an unexpected binding of this antibody with cells containing glycogen and other PAS positive substances was found, which could be abolished by adsorption of the anti-filaggrin antibody with glycogen or pretreatment of the sections with diastase.Keywords
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