Partial synthesis of [17-13C; 15,17-3H]gibberellin A29 from gibberellin A3

Abstract

The preparation of [17-¹³C]gibberellin A₂₉, containing 96.8 atoms %¹³C, from gibberellin A₃ in fourteen steps in 0.55% overall yield is described. [17-¹³C; 15,17-³H]Gibberellin A₂₉, containing 90.6 atoms %¹³C and with a specific radioactivity of 29.8 mCi mmol^–1, is also described. The ready conversion of 2,O²-didehydrogibberellin A₂₉ by aqueous alkali to a known catabolite of gibberellin A₂₉ is noted.