Pharmacologic Trials in the Treatment of Cerebellar Tremor

Abstract

• We studied the effect of long-term administration of propranolol hydrochloride and isoniazid and the acute action of ethyl alcohol on cerebellar tremor in patients with multiple sclerosis and primary cerebellar degeneration in a placebocontrolled double-blind crossover test. None of the drugs decreased the severity of either static or kinetic cerebellar tremors.