Jaundice Due to Ectylurea

Abstract

SINCE the first report associating cholangiolitic hepatitis with administration of arsphenamine,¹ a growing list of drugs have been identified with the production of this clinical syndrome. Notable among these have been methyltestosterone² and chlorpromazine³ and, more recently, promazine.⁴ It is the purpose of this communication to report what is believed to be the first case attributable to a recently introduced drug, ectylurea (2-ethyl-cis-crotonyl-urea),§ which has received fairly widespread use and favorable comment as a tranquilizing drug.^{5 6 7} Case ReportA 35-year-old housewife was admitted to the United States Naval Hospital, St. Albans, New York, with the chief complaint of nausea and . . .