MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
Top Cited Papers
- 1 July 2011
- journal article
- research article
- Published by Elsevier in Cancer Cell
- Vol. 20 (1), 66-78
- https://doi.org/10.1016/j.ccr.2011.06.010
Abstract
No abstract availableKeywords
Funding Information
- Leukemia and Lymphoma Society
- Gabrielle’s Angel Foundation for Cancer Research
- American Cancer Society
- Deutsche Forschungsgemeinschaft (BU 1339/3-1)
- National Heart, Lung, and Blood Institute (K08 HL102264)
- National Institute of General Medical Sciences (GM083054)
- National Cancer Institute (1RC2CA148222, CA105423, CA140575, CA684841)
This publication has 47 references indexed in Scilit:
- GenePattern 2.0Nature Genetics, 2006
- Leukemogenic MLL Fusion Proteins Bind across a Broad Region of the Hox a9 Locus, Promoting Transcription and Multiple Histone ModificationsCancer Research, 2005
- A conserved, extended chromatin opening within α-globin locus during developmentExperimental Cell Research, 2005
- hDOT1L Links Histone Methylation to LeukemogenesisCell, 2005
- Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular ImmortalizationMolecular and Cellular Biology, 2004
- Structure of the Catalytic Domain of Human DOT1L, a Non-SET Domain Nucleosomal Histone MethyltransferaseCell, 2003
- vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineagesGenesis, 2002
- ALL-1 Is a Histone Methyltransferase that Assembles a Supercomplex of Proteins Involved in Transcriptional RegulationMolecular Cell, 2002
- MLL Targets SET Domain Methyltransferase Activity to Hox Gene PromotersMolecular Cell, 2002
- Molecular mechanisms of leukemogenesis mediated by MLL fusion proteinsOncogene, 2001