Chondroprotective effects of a proanthocyanidin rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes
Open Access
- 1 January 2007
- journal article
- Published by Springer Nature in Journal of Inflammation
- Vol. 4 (1), 16
- https://doi.org/10.1186/1476-9255-4-16
Abstract
The Amazonian medicinal plant Sangre de grado (Croton palanostigma) has traditional applications for the treatment of wound healing and inflammation. We sought to characterize two extracts (progrado and zangrado) in terms of safety and oligomeric proanthocyanidin chain length. Additionally progrado was evaluated for antioxidant activity and possible chondroprotective actions.Keywords
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