Ambient Air Pollution and the Risk of Acute Ischemic Stroke
Top Cited Papers
Open Access
- 13 February 2012
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Internal Medicine
- Vol. 172 (3), 229-234
- https://doi.org/10.1001/archinternmed.2011.732
Abstract
Daily changes in levels of ambient fine particulate matter (PM) air pollution (PM 2.5]) have been associated with higher risk of acute cardiovascular events, excess hospitalizations, and deaths.1 These cardiovascular effects of PM2.5 appear to be mediated through a combination of autonomic, hemostatic, inflammatory, and vascular endothelial disturbances with consequent changes in cardiac and vascular function.2-7 Relying on the current evidence, the US Environmental Protection Agency (EPA) regulates mean daily and annual PM2.5 levels. Whether the current regulatory standards are sufficient to protect public health remains controversial.8Keywords
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