DIETARY FACTORS IN THE PATHOGENESIS OF SIMPLE GOITER*†
- 1 November 1949
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 9 (11), 1069-1079
- https://doi.org/10.1210/jcem-9-11-1069
Abstract
The occurrence of a naturally occurring goitro-gen of the thiocarbonamide series, l-5-vinyl-2-thiooxazolidone, in turnip and rutabaga root is reported. The possible relationship of this or similar compounds to the pathogenesis of certain cases of simple goiter is discussed. It seems probable that a high intake of certain of these goitrogenic vegetables by man may result in thyroid enlargement.Keywords
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