Abstract
By means of gentle pressure on isolated guineapig islets, cells in an isolated state were obtained. The free islet cells could be classified as A1, A2 and B cells with the current staining methods. Determinations of the dry mass with a scanning interference microphotometer showed a significantly higher value in the A2 cells (1.95 x 10-10 g) as compared with the B cells (1.12 x lO-10 g). Various possibilities for utilizing the isolated islet cells for further analyses of the endocrine activity of the pancreas are discussed.