A Gastric Inhibitory Polypeptide. I. The Amino Acid Composition and the Tryptic Peptides

Abstract

The partial structure of a polypeptide with inhibitory activity for gastric secretion has been found to be Tyr–(Ala₂, Asx, Glx, Gly, Ile₂, Phe, Ser₂, Thr, Tyr)–Met–Asp–Lys–Ile–Arg–Gln–(Ala, Asx₂, Glx_2–3, Leu, Phe, Val, Trp)–Lys–Gly–Lys–Lys–Ser–Asp–Trp–Lys–His–(Asx, Ile, Thr, Gln).