Archaeological remains from the southern Californian desert region, spanning a period from 7000 B.C. to historic times, are segregated into four broad cultural horizons. The earliest certain evidences of human occupation consist of stone tools and weapons from the shore line of ancient Lake Mohave. The Lake Mohave artifacts comprise types designed primarily for hunting and related activities. Next in sequence are the lithic materials from Pinto Basin and other localities that demonstrate a mixed hunting-gathering economy. The third or Amargosa period is inadequately known. Triangular arrowpoints, pottery, and numerous seed-grinding implements distinguish the closing aboriginal phase. The major research needs are indicated.