Biological Properties of CELO Virus: Stability to Various Agents, and Electron-Microscopic Study

Abstract

Studies on the stability of CELO (chicken embryo lethal orphan) virus to some physical and chemical agents indicate that it is resistant to ethyl ether, chloroform, sodium desoxycholate, phenol, and 50% but not 100% ethyl alcohol. It is much more resistant to UV irradiation, but very much more sensitive to photodynamic inactivation, than Newcastle disease virus. Other physical properties were also investigated. Electron microscope studies suggest that CELO virus shares many properties with the adenovirus group, such as size, shape, and multiplication site. It appears to be nearly 70 mu in size, and without an envelope. Relations between CELO virus and adenoviruses are discussed.