Rheumatoid Factor and Immuno-Conglutinin Responses Following Various Vaccinations

Abstract

Rheumatoid factor and immunoconglutinin responses following various vaccinations [tetanus, salmonella, mumps, polio, smallpox] were studied in a series of 381 healthy military recruits. The results suggested that both types of reaction were related to the net immune response provoked by the vaccinations. The immuno-conglutinin response took place within 2 weeks, whereas 3-4 weeks were needed for the appearance of rheumatoid factors. Immunoconglutinin titer increases and positive rheumatoid factor reactions were not seen in the same persons.