Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas
- 13 October 2006
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 349 (1), 277-283
- https://doi.org/10.1016/j.bbrc.2006.08.046
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology
- Ministry of Health, Labour and Welfare
- Naito Foundation
This publication has 30 references indexed in Scilit:
- Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarraysHuman Molecular Genetics, 2005
- Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exonsGenomics, 2005
- A novel first exon of thePatched1gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functionsFEBS Letters, 2004
- Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 proteinOncogene, 2002
- Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephalyHuman Genetics, 2002
- Hedgehog signaling in animal development: paradigms and principlesGenes & Development, 2001
- The role of the human homologue of Drosophila patched in sporadic basal cell carcinomasNature Genetics, 1996
- Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus SyndromeScience, 1996
- Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma SyndromeCell, 1996
- Nevoid Basal-Cell Carcinoma SyndromeMedicine, 1987