Raman optical activity of simple chiral molecules; methyl and trifluoromethyl asymmetric deformations

Abstract

Raman circular intensity differential spectra between 80 and 2 000 cm^–1 of (–)-1-phenylethylamine, (+)-1-phenylethanol, (+)-2,2,2-trifluoro-1-phenylethanol, (+)-1-p-bromophenylethylamine, and (–)-N-benzyl-1phenylethylamine are presented, and several stereochemical correlations are pointed out. The spectrum of the p-bromo-species indicates that the previously reported identification of a couplet with the methyl asymmetric deformations should be used with caution. A couplet at about 520 cm^–1 in the spectrum of the trifluoromethyl species may originate from the analogous trifluoromethyl asymmetric deformations.