THE PERIPHERAL ACTION OF HEXAMETHONIUM AND OF PENTOLINIUM
Open Access
- 1 December 1958
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 13 (4), 480-484
- https://doi.org/10.1111/j.1476-5381.1958.tb00242.x
Abstract
The influence of hexamethonium and pentolinium on the responses of certain peripheral effector cells to adrenaline, noradrenaline or postganglionic stimulation was studied in the cat. The actions of adrenaline and noradrenaline on the blood vessels of a limb and of adrenaline and postganglionic stimulation on the nictitating membrane were increased after the administration of hexamethonium and pentolinium. This effect was considered to be due to sensitization of the peripheral effector cells. The possible significance of these findings is discussed.Keywords
This publication has 9 references indexed in Scilit:
- ROLE OF BUFFER MECHANISMS IN SYMPATHETIC DRUG ACTION1958
- [Classification of a group of serotonin antagonists, and analysis of the sites of the peripheral vascular action of serotonin].1957
- THE RELATIVE EFFECTS OF GANGLION‐BLOCKING COMPOUNDS ON THE SYMPATHETIC AND PARASYMPATHETIC GANGLIA SUPPLYING THE CAT HEARTBritish Journal of Pharmacology and Chemotherapy, 1956
- The Interruption of Ganglionic Transmission and Some of its ProblemsJournal of Pharmacy and Pharmacology, 1955
- [Potentiation by ganglion-blocking agents of the pressor response to adrenalin and acetylcholine].1955
- Correlation between membrane potential, spike discharge and tension in smooth muscleThe Journal of Physiology, 1955
- PERIPHERAL ACTION OF THE GANGLION BLOCKINC AGENTSThe Japanese Journal of Pharmacology, 1955
- POTENTIATION OF THE PRESSOR ACTION OF NORADRENALINE BY HEXAMETHONIUM, TETRAETHYL‐AMMONIUM, AND METHANTHELINEBritish Journal of Pharmacology and Chemotherapy, 1954
- Experiments on the post‐contraction hyperaemia of skeletal muscleThe Journal of Physiology, 1953