Intravascular Platelet Aggregation in the Heart Induced by Stress
- 1 February 1973
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 47 (2), 353-358
- https://doi.org/10.1161/01.cir.47.2.353
Abstract
Sixteen rats, stressed by immersion in ice-cold water for 25-45 min, were found to have platelet aggregates in myocardial small vessels on electron microscopic study. None of six similar nonstressed control rats had platelets in myocardial vessels. It is concluded that stress, probably via catecholamine secretion that enhances platelet stickiness, can induce intravascular platelet aggregation. It is possible that this mechanism plays a part in the relationship between stress and acute clinical myocardial infarction.Keywords
This publication has 19 references indexed in Scilit:
- The role of platelet aggregation in catecholamine-induced cardiac necrosis: Electron microscopic and drug studiesThe American Journal of Cardiology, 1972
- Trends in the development of antithrombotic agentsThe American Journal of Cardiology, 1971
- Psychosocial Forces in Myocardial Infarction and Sudden DeathCirculation, 1969
- THE ROLE OF THROMBOGENIC FACTORS IN ATHEROSCLEROSISAnnals of the New York Academy of Sciences, 1968
- The Pathology of Acute Coronary DeathActa Anaesthesiologica Scandinavica, 1968
- Catecholamine secretion and sympathetic nervous responses to emotion in men with and without angina pectorisAmerican Heart Journal, 1967
- Some Effects of Adrenaline and Anti-Adrenaline Compounds on Platelets in vitro and in vivoNature, 1963
- STRESS AND OCCLUSIVE CORONARY-ARTERY DISEASEThe Lancet, 1963
- Some similar effects after large doses of catecholamines and myocardial infarction in dogs∗The American Journal of Cardiology, 1960
- RELATIVE SIGNIFICANCE OF HEREDITY, DIET AND OCCUPATIONAL STRESS IN CORONARY HEART DISEASE OF YOUNG ADULTS BASED ON AN ANALYSIS OF 100 PATIENTS BETWEEN THE ACES OF 25 AND 40 YEARS AND A SIMILAR GROUP OF 100 NORMAL CONTROL SUBJECTSThe American Journal of the Medical Sciences, 1958