STAPHYLOCOCCAL TOXINS: I. FACTORS AFFECTING THE HEMOLYTIC ACTIVITY OF ALPHA TOXIN
- 1 February 1957
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 3 (1), 47-54
- https://doi.org/10.1139/m57-006
Abstract
The hemolytic activity of α-toxin of Micrococcus pyogenes var. aureus has been shown to be maximal at pH 6.8–7.0 in phosphate-buffered saline. Within the limits of 25 to 75% hemolysis there is a linear relationship between lysin concentration and extent of hemolysis after incubation for 15 minutes. Citrate and glucose have been shown to inhibit hemolysis by α-toxin. The manner in which the factors studied affect determination of α-toxin activity by a direct hemolysis procedure is discussed.Keywords
This publication has 4 references indexed in Scilit:
- CORYNEBACTERIUM PYOGENES TOXIN - WITH PARTICULAR REFERENCE TO ITS MEASUREMENT1953
- Kinetic Aspects of Hemolysis by the -Toxin of Clostridium Welchii and its Inhibition by AntitoxinThe Journal of Infectious Diseases, 1951
- Staphylococcal δ-hæmolysinThe Journal of Pathology and Bacteriology, 1950
- THE IMMUNOCHEMISTRY OF TOXINS AND TOXOIDS .5. THE SOLUBILITY OF STAPHYLOCOCCAL TOXIN IN METHANOL-WATER MIXTURES UNDER CONTROLLED CONDITIONS OF PH, IONIC STRENGTH, AND TEMPERATURE1948