Squamous cell carcinoma of the paranasal sinuses: The cleveland clinic experience 1977–1986
- 1 November 1989
- journal article
- Published by Wiley in The Laryngoscope
- Vol. 99 (11), 1130-1136
- https://doi.org/10.1288/00005537-198911000-00005
Abstract
Fifty-four of 103 malignancies of the paranasal sinuses treated at the Cleveland Clinic Foundation between 1977 and 1986 were squamous cell carcinomas. Six arose from the ethmoid sinus and 48 from the maxillary sinus. Of the maxillary sinus patients, 11 presented with T1 or T2 lesions, 20 with T3, 16 with T4, and 7 of these had nodal disease. Treatment was surgery and/or radiation therapy. There was local recurrence in 25 of 48 maxillary sinus patients and in 1 of 6 ethmoid patients. Overall 5-year survival was 38.2% in the maxillary sinus group: T1, 100.0%; T2, 85.7%; T3, 31.8%; and T4, 6.7%. Three of six patients with ethmoid tumors were cured. There was a statistical trend for better prognosis in those patients presenting with ethmoid primaries, with early lesions, treated with both radiation and surgery, and with history of inverting papilloma. There were complications of treatment in 10 patients, four of which resulted in death. Local control was the major problem for these patients; therefore, early detection and aggressive local treatment are desirable.Keywords
This publication has 14 references indexed in Scilit:
- Paranasal sinus malignancy: A comprehensive updateThe Laryngoscope, 1989
- The role of radiation therapy in treatment of malignant tumors of the paranasal sinusesThe Laryngoscope, 1984
- Squamous cell carcinoma of the maxillary sinus: Analysis of 66 casesHead & Neck Surgery, 1983
- Carcinoma of the Paranasal SinusesCancer, 1982
- Comparison of pre- and postoperative radiation in the combined treatment of carcinoma of maxillary sinusInternational Journal of Radiation Oncology*Biology*Physics, 1982
- Squamous Cell Carcinoma of the Maxillary SinusJAMA Otolaryngology–Head & Neck Surgery, 1981
- A Comparison of Treatment Modalities in Carcinoma of the Maxillary AntrumJAMA Otolaryngology–Head & Neck Surgery, 1980
- Carcinomas of the paranasal sinuses.A study of sixty-six casesCancer, 1977
- Combined surgery, radiotherapy, and regional chemotherapy in carcinoma of the paranasal sinusesCancer, 1970
- Squamous cell carcinoma of the maxillary antrumThe American Journal of Surgery, 1969