rorA mutation of Escherichia coli K-12 affects the recB subunit of exonuclease V

Abstract

The ATP-dependent nuclease, exonuclease V, of E. coli plays an important role in repair and recombination. The enzyme is composed of 2 subunits, one of which is the product of the recB and recC genes. Mapping and complementation experiments show that the rorA mutation, which results in radiation sensitivity but not the loss of recombination ability, is an allele of the recB gene.