EFFECT OF INTRA-OCULAR CONCENTRATION OF TYPHOID ANTIBODIES ON EXPERIMENTAL CORNEAL ULCERS

Abstract

The parenteral administration of various proteins for their nonspecific action on ocular inflammations is an accepted procedure. There have been many opinions expressed concerning the mode of action of this form of therapy. The consensus seems to emphasize a rise in the body temperature, which is considered to be well above the optimum for various organisms. Leukocytosis, which usually accompanies such therapy, is supposed to be beneficial and to indicate an increase in the general body defense. The other factors, such as an increase in the complement and antibody content of the blood, are grouped under the vague term "increased general resistance." Suffice it to say that the mechanism of the action of nonspecific therapy is not understood. So far as the eye is concerned, the rise in temperature could not benefit inflammations of the uveal tract by killing organisms, for the intra-ocular contents in a case of nonspecific