In earlier communications1 reference was made to the necessity of determining the daily amounts of urobilinogen in the feces and urine rather than attempting to interpret results obtained with qualitative tests. A method for the approximate quantitative estimation of the urobilinogen content was described, and in part II of this series of papers results were given which may be used as controls for the series to be presented here. The former group included normal persons, patients with mild infection, inanition, fever of various cause and anemia and hematopoietic disease of various types. The present investigation deals with the excretion of urobilinogen in the common forms of jaundice and hepatic disease. MATERIALS AND METHODS One hundred and thirty-five patients2 with jaundice or hepatic disease were studied with regard to the per diem excretion of urobilinogen. Their cases may be divided conveniently into seven groups, as follows: 1. Cholecystitis and