In the Laboratory of Surgical Pathology of Johns Hopkins Hospital is a tumor that was removed from the end of the little finger of the right hand in November 1924. This tumor, it is stated in the history, had no definite capsule. It was regarded as a neurofibroma, but the epithelioid cells and the vascular spaces in it could not be satisfactorily interpreted. Case 1.— The patient from whom this tumor was removed was a white woman, aged 38. Eight years before the tumor was removed the patient experienced severe, sharp pain in the tip of the little finger of the right hand. Five years later, that is, three years before removal, an incision was made and a curettement performed, as a diagnosis of periostitis ("a bone bruise") had been made. After this operation a distinct tumor was discovered. The tumor was very painful when pressed on, and definite painful