Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Top Cited Papers
Open Access
- 15 March 2012
- Vol. 149 (2), 410-424
- https://doi.org/10.1016/j.cell.2012.02.044
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetaseNucleic Acids Research, 2010
- Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling SymphonyJournal of Biological Chemistry, 2010
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino AcidsCell, 2010
- Autophagy in cellular growth controlFEBS Letters, 2010
- Orthogonal use of a human tRNA synthetase active site to achieve multifunctionalityNature Structural & Molecular Biology, 2009
- Molecular mechanisms of mTOR-mediated translational controlNature Reviews Molecular Cell Biology, 2009
- Re-evaluating the Roles of Proposed Modulators of Mammalian Target of Rapamycin Complex 1 (mTORC1) SignalingJournal of Biological Chemistry, 2008
- Aminoacyl tRNA synthetases and their connections to diseaseProceedings of the National Academy of Sciences, 2008
- Regulation of TORC1 by Rag GTPases in nutrient responseNature Cell Biology, 2008
- Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifsNature, 1990