A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
- 1 April 1999
- journal article
- review article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 57 (7), 727-741
- https://doi.org/10.1016/s0006-2952(98)00307-4
Abstract
No abstract availableKeywords
This publication has 123 references indexed in Scilit:
- Inhibition of DNA Unwinding and ATPase Activities of Human DNA Helicase II by Chemotherapeutic AgentsBiochemical and Biophysical Research Communications, 1997
- Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signalsCell, 1995
- P‐glycoprotein and alterations in the glutathione/glutathione‐peroxidase cycle underlie doxorubicin resistance in HL‐60‐R, a subclone of the HL‐60 human leukemia cell lineInternational Journal of Cancer, 1993
- Induction of stable transcriptional blockage sites by Adriamycin: GpC specificity of apparent Adriamycin-DNA adducts and dependence on iron(III) ionsBiochemistry, 1990
- Free radicals in anticancer drug pharmacologyChemico-Biological Interactions, 1989
- Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of actionBiochemistry, 1987
- Prevention of doxorubicin-induced killing of MCF-7 human breast cancer cells by oxygen radical scavengers and iron chelating agentsBiochemical and Biophysical Research Communications, 1986
- Binding mode of chemically activated semiquinone free radicals from quinone anticancer agents to DNAChemico-Biological Interactions, 1979
- Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycinBiochemical and Biophysical Research Communications, 1977
- Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agentsBiochemical and Biophysical Research Communications, 1977