Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds
- 15 April 2008
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 18 (8), 2628-2632
- https://doi.org/10.1016/j.bmcl.2008.03.027
Abstract
No abstract availableKeywords
This publication has 27 references indexed in Scilit:
- Potent, Selective and Cell Penetrant Inhibitors of SF-1 by Functional Ultra-High-Throughput ScreeningMolecular Pharmacology, 2008
- Identification of the First Synthetic Steroidogenic Factor 1 Inverse Agonists: Pharmacological Modulation of Steroidogenic EnzymesMolecular Pharmacology, 2007
- Identification of Small Molecule Agonists of the Orphan Nuclear Receptors Liver Receptor Homolog-1 and Steroidogenic Factor-1Journal of Medicinal Chemistry, 2006
- Crystallographic Identification and Functional Characterization of Phospholipids as Ligands for the Orphan Nuclear Receptor Steroidogenic Factor-1Molecular Cell, 2005
- Tissue-specific knockouts of steroidogenic factor 1Molecular and Cellular Endocrinology, 2004
- Orphan Nuclear Receptors: From Gene to FunctionEndocrine Reviews, 1999
- A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiationCell, 1994
- GAL4-VP16 is an unusually potent transcriptional activatorNature, 1988
- Total synthesis of quinocarcinol methyl esterJournal of the American Chemical Society, 1985
- Reaktionen der Trialkylsilyl‐trifluormethansulfonate, I. Synthese von Trialkylsilyl‐EnolethernEuropean Journal of Organic Chemistry, 1981