Blockage of chloride channels by HEPES buffer
- 23 February 1987
- journal article
- research article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 230 (1258), 93-100
- https://doi.org/10.1098/rspb.1987.0011
Abstract
Chloride channels of neurons of Drosophila are blocked when the cytoplasmic side of the membrane is exposed to the commonly used buffering agents 4-(2-hydroxyethyl)-1-piperazine ethanesulphonic acid (HEPES) and 4-morpholinepropanesulphonic acid (MOPS). In the presence of these compounds, chloride channels appear to function as a complex of multiple protochannels.This publication has 14 references indexed in Scilit:
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