It is said that one out of every ten adults has disease of the gall bladder and that one out of every thirteen has gallstones. If these figures are only approximately correct, there is certainly a remarkable discrepancy between the frequency of the occurrence and of the clinical recognition of chronic cholecystitis. This discrepancy is due partly to the ignorance of general practitioners concerning its frequency and partly to the obscurity of its symptoms. Yet when one's attention has been once directed to the subject, one is able to recognize certain symptoms which are very suggestive if not actually convincing. Prominent among these is indigestion or stomach trouble, with or without more or less epigastric distress, distention or uneasiness coming on several hours after a meal and accompanied or relieved by eructations of gas. Not uncommonly these symptoms of indigestion occur at night, often waking the individual from sleep toward