A survey of 61 outpatients admitted to a mental health center for the treatment of alcoholism determined that a majority of them (59 per cent) were clinically depressed. The depressive symptoms were rarely treated with anti-depressant agents and, at 1-year follow-up, were found to persist even though the patients had attended the standard treatment program for alcoholics. There is need for new treatment strategies that recognize the diagnostic heterogeneity of the alcoholic and that consider the use of appropriate psychopharmacological agents.