Until recently, the literature on the blood calcium and the therapeutic value of calcium in allergic conditions has been replete with contradictions. It is unnecessary in this work to do more than summarize various views. Briefly, there are those who believe that a calcium deficiency is present in allergy, and that calcium is indicated as an adjunct in treatment, and those who find no such deficiency and deny the value of calcium as a therapeutic agent in allergic conditions. Almost all the work since 1928 based on blood chemistry studies made since the development of the Kramer-Tisdall technic for calcium determination supports the latter point of view. Among the more recent workers who also review the literature to date are Cohen and Rudolph1 and Ramirez.2 In studies on a large number of various types of allergic conditions these workers found no calcium deficiency and no improvement or only