[Involvement of the spleen in congenital osteopetrosis of the "op" rat: corrective effect of thymus grafts].

Abstract

In the osteopetrotic mutant rat "op", the white pulp of the spleen is poor in T lymphocytes, while the red pulp is hyperplastic in reaction to the aplastic bone marrow. Grafting of normal thymus into the mutant corrects these anomalies.