In Vitro Approach to a Correlation of Cell Susceptibility to Viral Infection with HL-A Genotypes and Other Biological Markers

Abstract

In vitro tests of the susceptibility of 30 normal human fibroblast lines to infection by herpes hominis, adenovirus-7, echovirus-11 and measles viruses have shown significant variations in individual host susceptibility to infection by one or more of these agents. Resistance of an individual cell line to a given virus appears to be specific for that virus, and is not necessarily associated with resistance of the same cells to other viruses.