Immunofluorescent patterns and specificity of human antinuclear antibodies.

  • 1 September 1968
    • journal article
    • Vol. 3 (7), 641-56
Abstract
Immunofluorescent antinuclear antibody tests were performed on selected sera using leucocytes and rat liver sections, and the patterns of staining compared. Antibody to DNA was detected by immunodiffusion, complement fixation and radioimmunoelectrophoresis. Specificity of reactions was determined by digestion of nuclear substrate with DNAse, RNAse and trypsin.