Assessing Vascular Permeability during Experimental Cerebral Malaria by a Radiolabeled Monoclonal Antibody Technique
Open Access
- 1 May 2001
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 69 (5), 3460-3465
- https://doi.org/10.1128/iai.69.5.3460-3465.2001
Abstract
Vascular endothelial integrity, assessed by Evans blue dye extrusion and radiolabeled monoclonal antibody leakage, was markedly compromised in the brain, lung, kidney, and heart duringPlasmodium bergheiinfection, a well-recognized model for human cerebral malaria. The results for vascular permeability from both methods were significantly (P< 0.001) related.Keywords
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