ADMINISTRATION OF THIONIN AND METHYL VIOLET IN INTESTINAL BRUCELLA INFECTION

Abstract

The notably unsatisfactory state of our knowledge of the treatment of undulant fever makes any contribution that seems at all hopeful worthy of further consideration. It is with this in mind that our present method of treating cases is presented, in the hope that it may be tried in resistant cases elsewhere. The description by Amoss and Poston¹of a method for isolatingBrucellafrom the stools has made it possible to follow the results of treatment. Several of our cases have persistently shownBrucella abortusin the stools for long periods and after cultures from the blood and other body fluids had become negative. This has been true even when the blood serum showed a low agglutinin titer forBrucella abortus, and consequently the stool culture in these cases was the only method by which a positive diagnosis could be made. Huddleson²described the use of methyl