The Newer Cephalosporins

Abstract

A host of new semisynthetic penicillins, some differing considerably both in antibacterial spectrums and in pharmacologic properties from the prototype (penicillin G), were introduced in the early 1960's. Similarly, the first half of the 1970's has seen the development and marketing of a bewildering array of semisynthetic cephalosporin derivatives. The latter do not, however, appear to have provided quite the wide variation in properties and clinical utility from their prototype (cephalothin) as was true of the penicillins.The rapid succession of new cephalosporin derivatives in the past several years has made the practicing physician's task rather formidable — not only . . .