Hybridization of mitochondrial RNA with mitochondrial and nuclear DNA in agar.
- 1 January 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 55 (1), 114-119
- https://doi.org/10.1073/pnas.55.1.114
Abstract
Mitochondrial RNA has been isolated from mouse brain and liver, essentially free of contamination by other cytoplasmic RNA''s. Cross-matching and competition experiments have shown that 2 components may exist in the RNA from mitochondria, one of which is coded by nuclear DNA and the other by mitochondrial DNA. No hybridization was found between mitochondrial and nuclear DNA. It is suggested on these bases that the mitochondrial DNA represents a unique material, in part at least unrelated to nuclear DNA.Keywords
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