Electron Microscopic Characterization of Lipoproteins from Patients with Familial Type III Hyperlipoproteinaemia
- 1 February 1976
- journal article
- research article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 6 (1), 307-310
- https://doi.org/10.1111/j.1365-2362.1976.tb00525.x
Abstract
The lipoproteins of very low density, low density and intermediate density were isolated by zonal ultracentrifugation from the plasma of subjects with familial type III hyperlipoproteinemia and studied by EM. Each of these lipoproteins exhibited a spherical shape when free-standing. The very low density, low density and intermediate density lipoproteins ranged in diameter from 31-80, 17-23 and 21-35 nm, respectively. These results are consistent with previous findings that the intermediate density lipoprotein particles characteristic of plasma from type III subjects exhibit properties which are intermediate between those of very low density and low density lipoproteins.Keywords
This publication has 8 references indexed in Scilit:
- Type III HyperlipoproteinemiaPublished by Springer Nature ,1976
- Lipoprotein of the Density 1. 006–1. 020 in the Plasma of Patients with Type III Hyperlipoproteinaemia in the Postabsorptive StateEuropean Journal of Clinical Investigation, 1975
- Isolation and analysis of human plasma lipoproteins accumulating postprandial in an intermediate density fraction (d 1.006–1.019 g/ml)Clinica Chimica Acta; International Journal of Clinical Chemistry, 1974
- Primary Dysbetalipoproteinemia: Predominance of a Specific Apoprotein Species in Triglyceride-Rich LipoproteinsProceedings of the National Academy of Sciences, 1973
- Heterogeneity of human plasma very low density lipoproteins. Separation of species differing in protein componentsBiochemistry, 1973
- The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observationsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972
- Application of Electron Microscopy to the Study of Plasma Lipoprotein Structure1 1This work was supported by Research Grants HE 12710–02 and HE 10878–05 from the National Heart and Lung Institute, U. S. Public Health Service, Bethesda, Maryland, and by the U. S. Atomic Energy Commission.Published by Elsevier ,1972
- A lipoprotein characterizing obstructive jaundice. I. Method for quantitative separation and identification of lipoproteins in jaundiced subjectsJCI Insight, 1969