Gossypol binds to a high‐affinity binding site on human serum albumin
- 27 June 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 157 (1), 28-30
- https://doi.org/10.1016/0014-5793(83)81109-0
Abstract
The triterpene gossypol competes with bilirubin for a high-affinity binding site on human serum albumin. Similar competition between bilirubin and gossypol occurs in the binding of these ligands to the glutathione S-transferases from human liver and placenta. In each case, gossypol and bilirubin exhibit similar binding constants. The binding properties of gossypol may generally mimic those of bilirubin.Keywords
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