Adaptation of membrane lipids to alcohols
- 1 February 1976
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 125 (2), 670-678
- https://doi.org/10.1128/jb.125.2.670-678.1976
Abstract
The effects of alcohols of different chain lengths on the fatty acid composition of Escherichia coli K-12 were examined. These cells apparently radically change their fatty acid composition when grown in the presence of alcohols. These changes represent an adaptive membrane alteration compensating for the direct physicochemical interaction of alcohols with the membrane. Similar adaptive responses of membrane lipids are proposed as a possible biochemical basis for tolerance to alcohol and related drugs.This publication has 33 references indexed in Scilit:
- Metabolic Alterations of Fatty AcidsAnnual Review of Biochemistry, 1974
- Alcoholism and animalsPreventive Medicine, 1974
- The unsaturated fatty acid requirement in Escherichia coli Temperature dependence and total replacement by branched-chain fatty acidsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Role of lipid-phase transitions in the regulation of the (sodium + potassium ion)-dependent adenosinetriphosphataseBiochemistry, 1973
- The effects of long-chain alcohols on membrane lipids and the (Na+ + K+)-ATPaseBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Mesomorphic behaviour of some phospholip1ds with aliphatic alcohols and other non-ionic substancesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
- The effects of alcohols on lipid bilayers: A spin label studyBiochimica et Biophysica Acta (BBA) - Biomembranes, 1972
- Alcoholism, Alcohol, and DrugsScience, 1971
- The interaction of small molecules with spin-labelled erythrocyte membranesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1970
- Thermal analysis of lipids, proteins and biological membranes a review and summary of some recent studiesChemistry and Physics of Lipids, 1969