Citrate Lithiasis in the Rat
- 30 November 1951
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 167 (3), 698-702
- https://doi.org/10.1152/ajplegacy.1951.167.3.698
Abstract
Urinary lithiasis was produced in a large number of young rats by feeding them low P rations of approx. normal Ca content. The frequency of its occurrence was increased by feeding Na bicarbonate or potentially alkaline salts. It was entirely prevented by the feeding of adequate amts. of phosphate. Calculi produced on the basal ration having low P and adequate Ca consisted largely of Ca citrate, but with the feeding of additional alkali their citric acid content was reduced, their Ca content was increased, and carbonate and phosphate appeared as additional constituents.Keywords
This publication has 3 references indexed in Scilit:
- Study of Experimental Urinary Calculi: II. Quantitative Microchemical, Spectrographic, and Citric Acid Analyses of Albino Rat Calculi, with a Preliminary Apatite ReportJournal of Urology, 1945
- The Relation Between the Urinary Excretion of Citric Acid and Calcium; Its Implications for Urinary Calcium Stone FormationScience, 1942
- THE OCCURRENCE OF CITRIC ACID IN URINE AND BODY FLUIDSAmerican Journal of Physiology-Legacy Content, 1934