In vitro culture of functional human thymic epithelium.
- 1 February 1975
- journal article
- Vol. 19 (2), 281-7
Abstract
Cultures of pure epithelial cells have been obtained from human thymus. Incubation of spleen cells from adult thymectomized mice on these cultures rendered RFC sensitive to inhibition by anti-theta serum, whereas no effect was obtained with fibroblasts or spleen cell cultures. The fact that theta conversion was obtained when spleen cells were incubated in the thymic culture placed within a Millipore chamber indicates that theta conversion was due to the effect of a humoral factor.This publication has 14 references indexed in Scilit:
- Studies on thymus products. 3. Epithelial origin of the serum thymic factor.1974
- Thymus reticulum cell cultures confer T cell properties on spleen cells from thymus‐deprived animalsEuropean Journal of Immunology, 1973
- INDUCTION OF T LYMPHOCYTES FROM PRECURSOR CELLS IN VITRO BY A PRODUCT OF THE THYMUSThe Journal of Experimental Medicine, 1973
- IN-VITRO DEMONSTRATION OF THYMIC HORMONE IN THE MOUSE BY CONVERSION OF PRECURSOR CELLS INTO LYMPHOCYTESThe Lancet, 1973
- Purification and Biological Activity of Thymosin, a Hormone of the Thymus GlandProceedings of the National Academy of Sciences, 1972
- Mechanism of complement action in rosette inhibition and lymphocytotoxicity of antilymphocyte serum.1972
- Appearance of T-cell Markers in Bone Marrow Rosette-Forming Cells after Incubation with Thymosin, a Thymic HormoneProceedings of the National Academy of Sciences, 1971
- Surface Antigenic Markers for Distinguishing T and B Lymphocytes in MiceImmunological Reviews, 1971
- STUDIES ON SOME PHYSICOCHEMICAL PROPERTIES OF A THYMUS HUMORAL FACTOR CONFERRING IMMUNOCOMPETENCE ON LYMPHOID CELLSThe Journal of Experimental Medicine, 1970
- INCORPORATION OF SULFATE BY THE MOUSE THYMUS: ITS RELATION TO SECRETION BY MEDULLARY EPITHELIAL CELLS AND TO THYMIC LYMPHOPOIESISThe Journal of Experimental Medicine, 1968