AN UNUSUAL DNA EXTRACTED FROM BACTERIA INFECTED WITH PHAGE T2
- 1 March 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 49 (3), 366-372
- https://doi.org/10.1073/pnas.49.3.366
Abstract
Deoxyribonucleic-acid (DNA) from T2-infected bacteria in which the terminal stages of phage growth are prevented by an inhibitor of protein synthesis shows properties indicative of a high molecular weight strong binding to a column of basic protein, rapid sedimentation and extreme fragility under hydrodynamic shear. It resembles the DNA in phage particles with respect to nucleotide composition, fragility per unit length and susceptibility to thermal denaturation; but it differs in that it shows signs of physical inhomo-geneity and incomplete double-helical structure.Keywords
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