Innate lymphoid cells — a proposal for uniform nomenclature
Top Cited Papers
- 7 January 2013
- journal article
- review article
- Published by Springer Nature in Nature Reviews Immunology
- Vol. 13 (2), 145-149
- https://doi.org/10.1038/nri3365
Abstract
Innate lymphoid cells (ILCs) are a family of developmentally related cells that are involved in immunity and in tissue development and remodelling. Recent research has identified several distinct members of this family. Confusingly, many different names have been used to characterize these newly identified ILC subsets. Here, we propose that ILCs should be categorized into three groups based on the cytokines that they can produce and the transcription factors that regulate their development and function.Keywords
This publication has 50 references indexed in Scilit:
- The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid CellsImmunity, 2012
- The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid CellsImmunity, 2012
- The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell MaturationImmunity, 2012
- Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunityNature Immunology, 2011
- An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammationNature Immunology, 2011
- Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunityNature Immunology, 2011
- CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the GutImmunity, 2010
- Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate LymphocytesImmunity, 2010
- Epigenetic Instability of Cytokine and Transcription Factor Gene Loci Underlies Plasticity of the T Helper 17 Cell LineageImmunity, 2010
- Nuocytes represent a new innate effector leukocyte that mediates type-2 immunityNature, 2010