An Investigation into the Effects of 2:2-bis-(p-chlorophenyl)-1:1-dichloroethane (D.D.D.) on the Mouse Adrenal Cortex
- 1 September 1954
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 6 (1), 625-628
- https://doi.org/10.1111/j.2042-7158.1954.tb10996.x
Abstract
Summary White male mice maintained on a diet containing 0·1 per cent, of 2:2-bis-(p-chlorophenyl)-1:1-dichloroethane and mice injected subcutaneously thrice weekly with an oily solution at a dosage of 20 mg./100 g. of body weight, for periods up to 6 weeks failed to exhibit a significantly decreased response to cold stress as compared with the untreated controls. The drug did not significantly decrease the adrenal weights of the treated groups.Keywords
This publication has 6 references indexed in Scilit:
- Effect of 2,2-bis(Parachlorophenyl)-l,l-Dichloroethane (DDD) on the Adrenal Cortex of the RatNature, 1953
- EFFECT OF HYPOPHYSECTOMY, DDD TREATMENT, AND SURGICAL TRAUMA ON THE OXYGEN CONSUMPTION OF THE VARIOUS ZONES OF THE ADRENAL CORTEX1Endocrinology, 1953
- Influence of the Drug DDD on Adrenal Cortical Function in Adult Rats.Experimental Biology and Medicine, 1953
- D.D.D. THERAPY IN CUSHING'S SYNDROMEThe Lancet, 1953
- EFFECT OF PARTIAL ADRENAL CORTICAL ATROPHY ON THE COURSE OF ALLOXAN DIABETES*Endocrinology, 1952
- Tissue Distribution and Elimination of DDD and DDT Following Oral Administration to Dogs and Rats.Experimental Biology and Medicine, 1949